HLA Class II alleles, tissue damage and antibody response in COVID-19

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Vanaga, Ieva; Kolesova, Oksana; Kolesovs, Aleksandrs; Viksna, Ludmila, 2022, "HLA Class II alleles, tissue damage and antibody response in COVID-19", https://doi.org/10.48510/FK2/ATVBQE, Dataverse, V1, UNF:6:IsOt6lNIEtS+a+CbZl83Sw== [fileUNF]

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Description	Data include following variables: Demographics, comorbidities, classification of COVID-19 severity accordantly the World Health Organization definition, duration of hospitalization, day of hospitalization. Blood cells: white cells count (WBC), erythrocytes (RBC), neutrophils (Neu), lymphocytes (Ly), platelet count (PLT), CD4+ T lymphocytes, CD8+ T lymphocytes. Inflammatory indicators: erythrocyte sedimentation rate (ESR), C-reactive protein (CRP), ferritin, interleukin-6 (IL-6). Tissue damage indicators: alanine aminotransferase (ALT), aspartate aminotransferase (AST), lactate dehydrogenase (LDH), and gamma-glutamyl transferase (GGT). Renal function indicator: creatinine. Coagulation tests: D-dimer, prothrombin index at admission to the hospital. Fibrosis and apoptosis markers: Hyaluronic acid (HA), Cytokeratin 18 (CK18), and Caspase-cleaved cytokeratin 18 (CK18-M30) in serum at admission to the hospital. The minimal oxygen saturation (SpO2) during hospitalization. HLA Class II alleles in three loci: HLA-DRB1, -DQA1, -DQB1. Anti-SARS-CoV-2 IgM and IgG antibodies, day of antibodies tests.
Subject	Medicine, Health and Life Sciences
Keyword	COVID-19, HLA, clinical tests, fibrosis, apoptosis, antibodies

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	Data_HLA_Covid_VPP6_3.tab Tabular Data - 15.2 KB Published May 3, 2022 0 Downloads 39 Variables, 101 Observations UNF:6:IsOt6lNIEtS+a+CbZl83Sw==	Access File File Access Restricted Request Access Download Metadata Data File Citation EndNote XML RIS BibTeX

Citation Metadata

Dataset Persistent ID	doi:10.48510/FK2/ATVBQE
Publication Date	2022-05-03
Title	HLA Class II alleles, tissue damage and antibody response in COVID-19
Author	Vanaga, Ieva (Riga Stradins University, Department of Infectious diseases) - ORCID: 0000-0001-7667-2469 Kolesova, Oksana (Riga Stradins University, Institute of Microbiology and Virology) - ORCID: 0000-0002-2846-1242 Kolesovs, Aleksandrs (Riga Stradins University, Department of Infectious diseases) - ORCID: 0000-0003-4470-2453 Viksna, Ludmila (Riga Stradins University, Department of Infectious diseases) - ORCID: 0000-0002-1826-9230
Contact	Use email button above to contact. Kolesova, Oksana (Riga Stradins University, Institute of Microbiology and Virology) Viksna, Ludmila (Riga Stradins University, Department of Infectious diseases)
Description	Data include following variables: Demographics, comorbidities, classification of COVID-19 severity accordantly the World Health Organization definition, duration of hospitalization, day of hospitalization. Blood cells: white cells count (WBC), erythrocytes (RBC), neutrophils (Neu), lymphocytes (Ly), platelet count (PLT), CD4+ T lymphocytes, CD8+ T lymphocytes. Inflammatory indicators: erythrocyte sedimentation rate (ESR), C-reactive protein (CRP), ferritin, interleukin-6 (IL-6). Tissue damage indicators: alanine aminotransferase (ALT), aspartate aminotransferase (AST), lactate dehydrogenase (LDH), and gamma-glutamyl transferase (GGT). Renal function indicator: creatinine. Coagulation tests: D-dimer, prothrombin index at admission to the hospital. Fibrosis and apoptosis markers: Hyaluronic acid (HA), Cytokeratin 18 (CK18), and Caspase-cleaved cytokeratin 18 (CK18-M30) in serum at admission to the hospital. The minimal oxygen saturation (SpO2) during hospitalization. HLA Class II alleles in three loci: HLA-DRB1, -DQA1, -DQB1. Anti-SARS-CoV-2 IgM and IgG antibodies, day of antibodies tests.
Subject	Medicine, Health and Life Sciences
Keyword	COVID-19 HLA clinical tests fibrosis apoptosis antibodies
Language	English
Production Date	2022-04-19
Grant Information	Latvian Council of Science: VPP-COVID-2020/1-0023
Depositor	Kreišmanis, Ingmārs
Deposit Date	2022-04-20
Date of Collection	Start: 2020-09-01 ; End: 2021-05-31
Kind of Data	Clinical data
Software	SPSS

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